聚乙烯吡咯烷酮
十二烷基硫酸钠
肺表面活性物质
溴化物
金属有机骨架
检出限
电催化剂
生物传感器
化学
核化学
材料科学
色谱法
电极
纳米技术
无机化学
有机化学
电化学
生物化学
吸附
物理化学
作者
P. Arul,Sheng‐Tung Huang,Veerappan Mani
标识
DOI:10.1016/j.apsusc.2021.149827
摘要
From a clinical point of view, excessive bilirubin (BR) level in the human body can cause diseases such as jaundice, liver failure, and mental disorders. Therefore, a quantitative detection of BR is an important indicator of liver health. In this study, a non-enzymatic detection of BR biosensor is reported based on a tunable morphological structure of various surfactant-capped Cu-metal organic frameworks (Cu-MOFs). The Cu-MOF was prepared by a solvothermal synthetic route. The structures and properties were tuned by varying different surfactants including polyvinylpyrrolidone (PVP), sodium dodecyl sulfate (SDS), cetyltrimethylammonium bromide (CTAB) and sodium hydroxymethylglycinate (SHMG). The prepared [email protected] were monitored by FE-SEM and they showed well-defined colloidosomes, spherical, dot-spherical and sponge-like morphological structures. Under optimized acquisition parameters, the catalytic performance of the different [email protected] MOF was as follows: Cu-MOF < [email protected] < [email protected] < [email protected] < [email protected] A wide linear range (1 nM–100 µM) and a low LOD (124 pM) was obtained for BR quantifications at [email protected]/GCE. The [email protected] was shown to be an excellent interference-free electrocatalyst against BR. Finally, the modified electrode was effectively used for the quantitative determination of BR in the sample of biological human fluids, and the obtained results were validated by spectrophotometer method.
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