红细胞生成
造血
免疫学
红细胞
肝病
胎儿
细胞因子
干细胞
生物
细胞生物学
贫血
医学
遗传学
内科学
怀孕
生物化学
作者
Yuanbin Song,Liang Shan,Rana Gbyli,Wei Liu,Till Strowig,Amisha Patel,Xiaoying Fu,Xiaman Wang,Mina L. Xu,Yimeng Gao,Ashley Qin,Emanuela M. Bruscia,Toma Tebaldi,Giulia Biancon,Padmavathi Mamillapalli,David Urbonas,Elizabeth E. Eynon,David G. Gonzalez,Jie Chen,Diane S. Krause
出处
期刊：Science
[American Association for the Advancement of Science]
日期：2021-03-05
卷期号：371 (6533): 1019-1025
被引量：36
标识
DOI：10.1126/science.abe2485
摘要
mice resulted in vaso-occlusion that replicated acute SCD pathology. Combined liver-cytokine-humanized mice will facilitate the study of diseases afflicting RBCs, including bone marrow failure, hemoglobinopathies, and malaria, and also preclinical testing of therapies.
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