血脑屏障
受体
运输机
药物输送
纳米医学
靶向给药
神经科学
生物
药品
纳米技术
药理学
中枢神经系统
材料科学
生物化学
纳米颗粒
基因
作者
Rui Pedro Moura,Cláudia Martins,Soraia Pinto,Flávia Sousa,Bruno Sarmento
标识
DOI:10.1080/17425247.2019.1583205
摘要
Nanomedicine may be particularly useful in brain drug delivery, mainly due to the possibility of functionalizing nanoparticles to target specific receptors/transporters. Since the BBB is endowed with numerous receptors and transporters responsible for regulating the proper metabolic activity of the brain, their targeting can be a promising bypass strategy to circumvent the hurdle that the BBB represents for brain drug delivery.
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