重编程
线粒体
细胞生物学
功能(生物学)
免疫疗法
细胞命运测定
生物
T细胞
细胞
免疫学
免疫系统
遗传学
转录因子
基因
作者
Xia Liu,Guangyong Peng
标识
DOI:10.1038/s41590-020-00861-6
摘要
An investigation of the molecular processes of mitochondrial reprogramming and metabolic stress in antigen-experienced T cells within tumor microenvironments reveals mechanisms responsible for T cell exhaustion and dysfunction and facilitates the development of new strategies for tumor immunotherapy.
科研通智能强力驱动
Strongly Powered by AbleSci AI