Clinical application and development of vitamin detection

Vitamin is one of the essential nutrients of human body. Monitoring the level of the vitamin receives more and more attention clinically. Common ways of vitamin detection include microbiological method, fluorescence analysis, immunological method, high performance liquid chromatography, liquid chromatography-mass spectrometry, electrochemical method and so on. In addition, there′re still many disputes on the reference interval of vitamins, the medical decision level and the specific reference intervals for different groups. Therefore, establishing a standardized method of vitamin detection is an urgent problem to be solved.(Chin J Lab Med, 2018, 41: 341-343) Key words: Vitamin; Chromatography, high pressure liquid; Tandem mass spectrometry; Electrochemical techniques