医学
胎盘植入
子宫动脉栓塞术
优势比
置信区间
产科
子宫切除术
妇科
子宫动脉
怀孕
回顾性队列研究
胎盘
胎儿
外科
妊娠期
内科学
生物
遗传学
作者
Mariko Jitsumori,Shinya Matsuzaki,Masayuki Endo,Takeya Hara,Takuji Tomimatsu,Shinya Matsuzaki,Tetsuo Miyake,Tsuyoshi Takiuchi,Aiko Kakigano,Kazuya Mimura,Eiji Kobayashi,Yutaka Ueda,Tadashi Kimura
摘要
Background: Uterine artery embolization (UAE) is used to treat severe postpartum hemorrhage (PPH).According to a few studies, UAE for PPH was associated with preterm birth, fetal growth restriction (FGR), and placenta accreta spectrum (PAS) in subsequent pregnancies.These previous studies, however, lacked controls, and to the best of our knowledge, no systematic literature reviews have been conducted thus far.We report the results of our retrospective case-control study of pregnancies after UAE at a single center and include a literature review to evaluate the risk of PAS in pregnancies after UAE.Methods: We retrospectively reviewed data from deliveries at our hospital between January 2012 and October 2017.We divided the delivery data into cases with previous UAEs performed for PPH (the post-UAE group) and those without UAEs (the non-UAE group, which included women without previous PPH).We defined PAS as cases in which hysterectomy was performed and pathological examination confirmed the diagnosis.Results are presented as odds ratios (ORs) with 95% confidence intervals (95% CIs).Results: We used data from 3155 patients in this study, of whom 16 patients had undergone UAE (post-UAE group) and 3139 had not (non-UAE group).We found no differences between the groups in terms of frequency of preterm births (12.5% versus 14.2%, respectively; OR, 0.863; 95% CI, 0.218 to 3.414; P = 0.84) or FGR (6.2% versus 10.0%, respectively; OR, 0.602; 95% CI, 0.104 to 3.584; P = 0.61).However, cases of PAS were significantly more common in the post-UAE group (37.5%) than in the non-UAE group (1.2%; OR, 50.303; 95% CI, 17.38 to 145.592; P < 0.01).Conclusion: Our results suggest that previous UAE is a significant risk factor for PAS.
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