Synthesis of Tetrakis-Tetrazole via a Repetitive MCR

The synthesis of novel and complex molecules of tetrakis-tetrazole was done via a Ugi-azide repetitive reaction from easily accessible starting materials in good yields. The use of orthogonal bifunctional reagents in isocyanide-based multicomponent reactions (IMCR) allowed the synthesis of structurally complex molecules in one pot manner. The molecules herein synthesized could have applications such as use as chelating agents and organocatalysts.