In this paper,the effect of heavy metal ion chromium(Ⅵ) with different mass concentrations on the growth and phycobiliprotein content of spirulina was studied.The results showed that chromium(Ⅵ) with proper concentration(10 mg/L) could increase the content of phycobiliprotein in spirulina,and accelerate the growth of spirulina.The content of phycobiliprotein in spirulina decreased and the growth of spirulina was inhibited when the concentration of chromium(Ⅵ) was above 10 mg/L.