乳腺癌
医学
抗药性
药品
癌症
肿瘤科
生物信息学
内科学
药理学
生物
遗传学
作者
Yuan Tang,Yue Wang,Mohammad F. Kiani,Bin Wang
标识
DOI:10.1016/j.clbc.2016.05.012
摘要
Breast cancer is the second leading cause of cancer death in women, affecting 1.7 million patients every year worldwide. As a result of its heterogeneous nature, the genetic profile and associated clinical feature varies greatly among different breast cancer subtypes. With the advancement of molecular biology, our understanding of breast cancer has improved greatly in recent years. In this review, we examine different types of breast cancer and summarize their clinical features, current treatment schemes, and potential drug resistance profiles in response to treatments. We believe that the understanding of the molecular mechanisms of each treatment and subsequent drug resistance development will eventually lead to the discovery of more effective and efficient second-line therapeutics.
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