医学
促性腺激素
排卵
戈塞雷林
促排卵
多囊卵巢病
卵巢过度刺激综合征
耐受性
HMG-CoA还原酶
溴隐亭
内科学
妇科
多囊卵巢
内分泌学
怀孕
激素
体外受精
胰岛素
催乳素
生物
不利影响
胰岛素抵抗
乳腺癌
酶
还原酶
癌症
生物化学
遗传学
出处
期刊:PubMed
[National Institutes of Health]
日期:1995-03-01
卷期号:47 (3): 93-7
被引量:2
摘要
To evaluate the efficacy and tolerability of treatment with goserelin + HMG vs bromocriptine + FSH + HMG in the induction of ovulation in patients with ovarian polycystosis.A randomized prospective study.Sterile women with ovarian polycystosis of the first type not responding to clomiphene citrate.Group A: bomocriptine + FSH + HMG (10 patients); Group B: goserelin depot (Zoladex) + HMG (18 patients).A greater percentage of ovulations, pregnancies and a higher success rate were obtained in Group B. The percentage of hyperstimulation was similar in both groups; there was a higher percentage of abortion in Group A. Cycle duration and the number of phials of gonadotropin were greater in Group B.Treatment with bromocriptine + gonadotropin remains the simplest; the treatment protocol based on geserelin depot + gonadotropin proved to be more efficacious.
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