The solute solubilities in supercritical CO2 with and without cosolvent are calculated with the MPR-2 model.By taking supercritical CO2 and cosolvent as a pseudocomponent and calculating equation parameter of the pseudocomponent by VDW-1 mixing rule,ternary supercritical system is simpled to binary supercritical system.The solubility data of 8 solutes in supercritical CO2,which are given including 268 data,are correlated and calculated.The calculated results agree fairly with the experimental results.