锌指
LIM域
无名指区
转录因子Sp1
锌指核酸酶
博士手指
无名指
锌
拟南芥
生物
锌指转录因子
转录因子
基因
细胞生物学
计算生物学
遗传学
化学
发起人
基因表达
突变体
有机化学
作者
Ji Huang,Jianfei Wang,Hongsheng Zhang
出处
期刊:PubMed
日期:2004-05-01
卷期号:26 (3): 414-8
被引量:18
摘要
Zinc finger protein is one of the important transcription factors with zinc finger domain that regulates gene expression in the eukaryotic organisms mainly by specifically interacting with target DNA sequence(cis-acting element). It could be divided into several types of zinc finger proteins, such as C2H2, C2HC, C2C2, C2HCC2C2, C2C2C2C2 etc, based on numbers and positions of Cys and His residues. Of these, C2H2 type zinc finger protein is the most clearly identified zinc finger transcription factor, with the wide existence in human, animals and plants. The characterized plant C2H2 zinc finger proteins are mainly involved in plant growth and development and the responses to environmental stresses. Up to now, more than 50 C2H2 zinc finger proteins have been reported in plants including petunia, Arabidopsis, wheat and rice, and most of them have the plant-specific QALGGH motif in zinc finger domain. This paper briefly introduces the structure, recognition of target-DNA sequence and functions involved in development or environmental stresses of plant C2H2 zinc finger proteins.
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