Cytosine refers to a number of small molecular peptide glycoproteins,which are produced by some immune or non-immune cells which have biological activity,relating with hematopoietic and inflammation and immune response.Therefore,cytokine assays in animal-induced immunosuppressive diseases has a very important clinical significance.This paper describes the detection of cytokines,cytokine-related immune suppression and the value of cytokines detection on chicken immunosuppression disease.