再生(生物学)
组织工程
生物医学工程
生物材料
纳米技术
材料科学
细胞生物学
医学
生物
作者
Mariana Sarai Silva-López,Luz Eugenia Alcántara-Quintana
出处
期刊:ACS applied bio materials
[American Chemical Society]
日期:2023-07-12
卷期号:6 (8): 2982-2994
被引量:2
标识
DOI:10.1021/acsabm.3c00284
摘要
Conditions, accidents, and aging processes have brought with them the need to develop implants with higher technology that allow not only the replacement of missing tissue but also the formation of tissue and the recovery of its function. The development of implants is due to advances in different areas such as molecular-biochemistry (which allows the understanding of the molecular/cellular processes during tissue repair), materials engineering, tissue regeneration (which has contributed advances in the knowledge of the properties of the materials used for their manufacture), and the so-called intelligent biomaterials (which promote tissue regeneration through inductive effects of cell signaling in response to stimuli from the microenvironment to generate adhesion, migration, and cell differentiation processes). The implants currently used are combinations of biopolymers with properties that allow the formation of scaffolds with the capacity to mimic the characteristics of the tissue to be repaired. This review describes the advances of intelligent biomaterials in implants applied in different dental and orthopedic problems; by means of these advances, it is expected to overcome limitations such as additional surgeries, rejections and infections in implants, implant duration, pain mitigation, and mainly, tissue regeneration.
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