索拉非尼
肝细胞癌
医学
内科学
胆固醇
癌症研究
载脂蛋白E
肿瘤科
疾病
作者
Shan Wan,Quan-Yao He,Yun Yang,Feng Liu,Xue Zhang,Xin Guo,Hui Niu,Yi Wang,Yi-Xuan Liu,Wen-Long Ye,Xiuming Li,Xue-Mei ZhuanSun,Pu Sun,Xiao‐Shun He,Guang Hu,Kai Breuhahn,Hua Zhao,Guo-Qiang Wu,Hua Wu
出处
期刊：Cancer Research
[American Association for Cancer Research]
日期：2024-03-12
卷期号：84 (11): 1872-1888
被引量：36
标识
DOI：10.1158/0008-5472.can-23-2889
摘要
Intracellular SPARC boosts cholesterol availability to fuel invasion and drug resistance in hepatocellular carcinoma, providing a rational approach to improve the treatment of advanced liver cancer.
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