Recent insights into the hepatoprotective potential of medicinal plants and plant‐derived compounds

药用植物 传统医学 植物化学 肝保护 芒果藤黄 萜类 生物 医学 植物 生物化学 谷胱甘肽
作者
Ramasamy Thilagavathi,Shabbah Begum,Sowfika Dharshini Varatharaj,Arun Kumar Balasubramaniam,Joselin Susan George,Chelliah Selvam
出处
期刊:Phytotherapy Research [Wiley]
卷期号:37 (5): 2102-2118 被引量:40
标识
DOI:10.1002/ptr.7821
摘要

Abstract Liver problems are a worldwide concern, and conventional medicinal therapies are ineffective. Hence, safeguarding the healthy liver is vital for good health and well‐being. Infections due to virus, immune problems, cancer, alcohol abuse, and an overdose of drugs are some of the causes of liver diseases. Antioxidants derived from medicinal plants and conventional dietary sources can protect the liver from damages caused by oxidative stress system and various chemicals. Plants and plant‐derived phytochemicals are appealing hepatoprotective agents since they have less side effects and still there is a lot of interest shown in using herbal tonics for treating liver disorders. This review therefore primarily focuses on newly discovered medicinal plants and compounds produced from plants that fall under the classifications of flavonoids, alkaloids, terpenoids, polyphenolics, sterols, anthocyanins, and saponin glycosides, all of which have the potential to be hepatoprotective. Hosta plantaginea, Ligusticum chuanxiong, Daniella oliveri, Garcinia mangostana, Solanum melongena, Vaccinium myrtillus, Picrorhiza kurroa, and Citrus medica are some potential plants having hepatoprotective effects. We conclude that these phytochemicals and the plant extracts listed above are used in the future to treat a variety of liver diseases, additional research is still needed to develop safer and more potent phytochemical drugs.
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