海洋酸化
适应(眼睛)
生物
表观遗传学
适应性反应
跨代表观遗传学
摄入
生态学
基因
气候变化
遗传学
生物化学
神经科学
作者
Min‐Sub Kim,Young Hwan Lee,Yoseop Lee,Eunjin Byeon,Duck-Hyun Kim,Minghua Wang,Atsushi Hagiwara,Manuel Aranda,Rudolf S.S. Wu,Heum Gi Park,Jae-Seong Lee
标识
DOI:10.1016/j.jhazmat.2023.132593
摘要
The adaptation of marine organisms to the impending challenges presented by ocean acidification (OA) is essential for their future survival, and mechanisms underlying OA adaptation have been reported in several marine organisms. In the natural environment, however, marine organisms are often exposed to a combination of environmental stressors, and the interactions between adaptive responses have yet to be elucidated. Here, we investigated the susceptibility of filter-feeding rotifers to short-term (ST) and long-term (LT) (≥180 generations) high CO2 conditions coupled with nanoplastic (NPs) exposure (ST+ and LT+). Adaptation of rotifers to elevated CO2 caused differences in ingestion and accumulation of NPs, resulting in a significantly different mode of action on in vivo endpoints between the ST+ and LT+ groups. Moreover, microRNA-mediated epigenetic regulation was strongly correlated with the varied adaptive responses between the ST+ and LT+ groups, revealing novel regulatory targets and pathways. Our results indicate that pre-exposure history to increased CO2 levels is an important factor in the susceptibility of rotifers to NPs.
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