美波利祖马布
医学
支气管扩张
恶化
哮喘
四分位间距
维持疗法
内科学
人口
嗜酸性
胃肠病学
嗜酸性粒细胞
肺
病理
化疗
环境卫生
作者
Sarah Bendien,Johannes A. Kroes,Lotte H.G. van Hal,Gert‐Jan Braunstahl,M.E.A.C. Broeders,Karen T.M. Oud,Kornelis W. Patberg,Frank W.J.M. Smeenk,Ilonka H.P.A.A. van Veen,Els J.M. Weersink,Karin B. Fieten,Simone Hashimoto,Anneke van Veen,Jacob K. Sont,Astrid van Huisstede,Marjo J.T. van de Ven,Bas Langeveld,Anke H. Maitland‐van der Zee,Anneke Ten Brinke
标识
DOI:10.1016/j.jaip.2023.05.041
摘要
This real-world study shows that anti-IL-5/5Ra therapy reduces exacerbation frequency and daily maintenance as well as the cumulative OCS dose in patients with severe eosinophilic asthma and comorbid bronchiectasis. Although it is an exclusion criterion in phase 3 trials, comorbid bronchiectasis should not preclude anti-IL-5/5Ra therapy in patients with severe eosinophilic asthma.
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