Effect of Graphene Oxide/Hydroxyapatite fine-grained AZ91D on blood compatibility and cytocompatibility

Abstract Magnesium alloy has excellent physical and mechanical properties and is expected to become a new generation of medical degradable materials. In this paper, the blood compatibility analysis of Graphene Oxide(GO) / Hydroxyapatite(HA)-AZ91D was carried out to improve the blood compatibility of magnesium alloy materials. AZ91D was used as the control group and GO/HA-AZ91D was used as the experimental group. The two samples were studied in vitro by hemolysis rate test, cell proliferation test, NO release and T-AOC test. The results combined with the work of the research group showed that the blood compatibility and cell compatibility of the GO/HA-AZ91D group were significantly improved, providing an effective idea for future corrosion resistant coatings on magnesium alloys.