生物
癌症研究
生物标志物
医学
细胞
胰腺癌
细胞生长
治疗方法
生物信息学
生物标志物发现
计算生物学
肿瘤细胞
钥匙(锁)
作者
Juanjuan Shi,X. Wang,Yingying Tang,Shixin Meng,Zhengyan Zhang,Ping Lu,Junyi Xu,Feier Yu,X. Wang,Zheng Wang,Yongwei Sun,Jing Xue
出处
期刊:Gut
[BMJ]
日期:2026-01-16
卷期号:: gutjnl-2025
标识
DOI:10.1136/gutjnl-2025-336460
摘要
Our work defines the LY6D+ gastric-like cell state as a key driver linking early pre-malignant heterogeneity to PDAC initiation and progression. LY6D represents a pan-stage therapeutic target and a candidate biomarker for early detection and therapeutic targeting.
科研通智能强力驱动
Strongly Powered by AbleSci AI