Biochemical Analysis of Human Seminal Plasma II. Protein, Non-Protein Nitrogen, Urea, Uric Acid and Creatine*

Seminal levels of protein, non-protein nitrogen (NPN), urea, uric acid and creatine were determined in human males divided as normal (Group I), azoospermia (Group II), infertile (Groups III, IV and V) with different sperm numbers and vasectomized (Group VI) cases. The geometrical mean level of seminal protein of Gr. I and Gr. V were significantly greater than that of Gr. IV. No significant difference in the levels of NPN and urea between any of the groups revealed. The seminal creatine level of Gr. I was significantly higher than that of Gr. III which in its turn was greater than that of Gr. VI, which recorded a value lowest of all the groups. Mean levels of uric acid of Gr. I was significantly greater than those of other five groups, taken individually. A direct correlation between uric acid level and sperm counts is an important observation that has emerged from this study.