胺化
立体选择性
化学
异氰酸酯
有机化学
舍曲林
全合成
催化作用
抗抑郁药
神经科学
生物
海马体
聚氨酯
作者
Sang Hwi Lee,In Su Kim,Qing Ri Li,Dong Guang,Lak Shin Jeong,Young Hoon Jung
摘要
The stereoselective amination of various chiral benzylic ethers using chlorosulfonyl isocyanate is developed, and the application of this method to the total synthesis of a potent antidepressant, (+)-sertraline, from readily available 1-naphthol is also described.
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