Chemoselective C(α)–C(β) bond cleavage of saturated aryl ketones with amines leading to α-ketoamides: a copper-catalyzed aerobic oxidation process with air

An unprecedented chemoselective C(α)–C(β) bond cleavage of simple saturated aryl ketones with amines leading to α-ketoamidesvia a copper-catalyzed aerobic oxidation process with air has been disclosed.