创伤性脑损伤
颅内压
医学
奇纳
动物研究
人体研究
荟萃分析
内科学
麻醉
精神科
心理干预
作者
Mohammad Nadir Haider,John J. Leddy,Andrea Hinds,Nell Aronoff,Diane C. Rein,David J. Poulsen,Barry Willer
出处
期刊:Brain Injury
[Informa]
日期:2018-04-27
卷期号:32 (7): 809-815
被引量:29
标识
DOI:10.1080/02699052.2018.1469045
摘要
Intracranial pressure (ICP) after mild traumatic brain injury (mTBI) is poorly studied due to lack of sensitive non-invasive methods. The purpose of this review was to summarize the existing knowledge of changes in ICP after mTBI. Literature selection: PubMed, Embase, CINAHL, and Scopus were searched by three reviewers independently up to December 2016.animal and human studies measuring ICP and brain oedema after an mTBI.moderate and severe forms of traumatic brain injury, repeat samples, and studies that measured ICP at the time of impact but not after. Study quality was assessed using Downs and Black criteria.Of 1067 papers, 9 studies were included. In human studies, one provided direct evidence on increased, one provided indirect evidence of increased, and two provided indirect evidence of decreased ICP. In animal studies, three studies provided direct evidence of increased, one provided indirect evidence of increased, and one provided indirect evidence of no change in ICP.The existing research suggests that there may be increased ICP after mTBI and animal studies suggest an elevation for days which returns to baseline, which corresponds with functional and symptomatic recovery. Future human studies using sensitive indirect methods to measure ICP longitudinally after mTBI are needed.
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