The article presents the results of Matlab simulations and experimental studies of non-contact influence of ultrasonic wave on laser beam.A role of the air-gap and the influence of the air-gap on laser-ultrasonic transmission in optical fiber were examined.Two optical fibers were used with air-gap between them.One fiber was attached to a laser diode and positioned to pass through a hole in a sandwich type transducer and in a velocity transformer.In the velocity transformer (at its end), after leaving small air-gap, to the end of the transformer, the other optical fiber is attached.The second fiber can interact with a given biological structure.