Sound transmission through an aircraft sidewall structure is investigated theoretically and experimentally in this paper. The studied configuration is composed of double-leaf lightweight partitions jointed with discrete placed rubber isolators. The effects of isolator stiffness, damping and spacing on sound transmission loss are calculated and tested. The influence of acoustic absorption treatment filled in the cavity is also included for a comparison. Furthermore, two methods which refers to space-harmonic and modal superposition expansions are employed for infinite and finite dimensions. At last, some approaches for sound transmission loss optimization are proposed.