A review of chemotherapy in gastric cancer

This paper compiles and reviews the data on chemotherapy with single drugs and multiple drug combinations in gastric cancer. Of the more than two dozen individual agents that have been used, only a few have been adequately evaluated, and just three (5-fluorouracil, Mitomycin C, and BCNU) exhibit clinically significant activity. The review points out the paucity of information on the efficacy of many standard anticancer drugs and the need for clinical studies designed specifically for stomach cancer.