医学
布比卡因
甲氧氯普胺
随机对照试验
止痛药
麻醉
外科
类阿片
临床试验
内科学
呕吐
受体
作者
Yar Luan Yeap,John W. Wolfe,Jennifer Stewart,Amy McCutchan,Gulraj Chawla,Bruce W. Robb,Bryan Holcomb,Ben Vickery
出处
期刊:Pain management
[Future Medicine]
日期:2022-01-01
卷期号:12 (1): 35-43
被引量:4
标识
DOI:10.2217/pmt-2021-0033
摘要
Aim: This study evaluated use of liposomal bupivacaine (LB) versus standard bupivacaine (SB) alone in quadratus lumborum (QL) blocks for laparoscopic colorectal surgery. Materials & methods: In this prospective, randomized controlled trial, patients received QL1 blocks with either LB (40 ml 0.125% SB plus 20 ml of LB) or SB (60 ml of 0.25% SB) with 30 ml per side. Opioid usage, pain scores, side effects and other medications were recorded. Results: For 78 patients (38 LB; 40 SB), all parameters were similar between groups, except that the LB group had a higher 48 h need for metoclopramide. Conclusion: LB provided no analgesic benefit over SB alone for QL blocks. Clinical Trials registration number: NCT03702621
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