骨关节炎
间充质干细胞
透明质酸
医学
骨髓
干细胞
病理
生物
解剖
细胞生物学
替代医学
作者
Abdulrazzaq Mahmod Suhaeb,Sangeetha Vasudevaraj Naveen,Azura Mansor,Tunku Kamarul
出处
期刊:PubMed
日期:2012-06-01
卷期号:50 (6): 383-90
被引量:6
摘要
Despite being a complex degenerative joint disease, studies on osteoarthritis (OA) suggest that its progression can be reduced by the use of hyaluronic acid (HA) or mesenchymal stem cells (MSC). The present study thus aims to examine the effects of MSC, HA and the combination of HA-MSC in treating OA in rat model. The histological observations using O'Driscoll score indicate that it is the use of HA and MSC independently and not their combination that delays the progression of OA. In conclusion, the preliminary study suggest that the use of either HA or MSCs effectively reduces OA progression better than their combined use.
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