Compared with the CPU which is good at handling logic complexity service,GPGPU(general purpose graphic processing unit) is suitable for large-scale parallel processing computing.The emergence of CUDA(compute unified device architecture) accelerates the expansion of application of GPGPU.We accelerate the implementation of AES algorithm based on GPGPU and CUDA and achieve a total throughput of 6~7Gbit/s.Regardless of the time of data loading and storing,a throughput of 20Gbit/s towards an input size over 1MB can be achieved.