Endoplasmic Reticulum Stress and Liver Disease

Endoplasmic reticula,widely distributed within cells,are important places for cell synthesis of proteins,lipids and sugars,and are closely related to transport and exchange of materials.Endoplasmic reticulum endoplasmic reticulum stress induced by steady imbalances(Endoplasmic reticulum stress,ERS),persistent stress can lead to apoptosis.A number of studies show endoplasmic reticulum stress and various liver diseases are closely related.This article reviews the correlation between endoplasmic reticulum stress and pathogenesis of liver disease.