Safety and efficacy of rapamycin-eluting stent coated with biodegradable polymer made in China

Objective:To evaluate the safety and efficacy of the second generation of rapamycin-eluting stent coated with biodegradable polymer(EXCEL) made in China.Methods:A cohort of 71 consecutive patients with coronary arterial disease was registered.The coronary angiographies were routinely performed and EXCELs were subsequently implanted to narrowed coronary arteries.In order to determine the survival rate without major adverse cardiac events(MACE) including cardiac death,myocardial infarction,and re-interventional therapy for target vessel,and the incidence of in-stent restenosis and stent thrombosis,the coronary angiography was carried out again in the subjects at sixteen to twenty-two months after initial coronary stenting.Results:A total of 113 stents were implanted in the 71 affected individualls,70 of whom underwent complete follow-up.It was observed that the survival rate of cases without MACE was 98.6%,the incidence of sub-acute thrombosis was 1.4%,and no in-stent restenosis occurred at an average of eighteen months following coronary stenting.Conclusion:Rapamycin-eluting stent coated with biodegradable polymer was safe and effective for the treatment of coronary artery disease.