神经重症监护
医学
精密医学
重症监护医学
个性化医疗
临床实习
冲程(发动机)
神经影像学
梅德林
疾病
生物信息学
病理
物理疗法
精神科
机械工程
政治学
法学
工程类
生物
作者
Nils Petersen,Kevin N Sheth,Ruchira Jha
出处
期刊:Stroke
[Ovid Technologies (Wolters Kluwer)]
日期:2023-05-01
卷期号:54 (5): 1392-1402
被引量:1
标识
DOI:10.1161/strokeaha.122.036402
摘要
Scientific advances have informed many aspects of acute stroke care but have also highlighted the complexity and heterogeneity of cerebrovascular diseases. While practice guidelines are essential in supporting the clinical decision-making process, they may not capture the nuances of individual cases. Personalized stroke care in ICU has traditionally relied on integrating clinical examinations, neuroimaging studies, and physiologic monitoring to develop a treatment plan tailored to the individual patient. However, to realize the potential of precision medicine in stroke, we need advances and evidence in several critical areas, including data capture, clinical phenotyping, serum biomarker development, neuromonitoring, and physiology-based treatment targets. Mathematical tools are being developed to analyze the multitude of data and provide clinicians with real-time information and personalized treatment targets for the critical care management of patients with cerebrovascular diseases. This review summarizes research advances in these areas and outlines principles for translating precision medicine into clinical practice.
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