后转座子
生物标志物
计算生物学
医学
第一行
生物信息学
生物
遗传学
内科学
基因组
基因
转座因子
作者
Aurélien J. Doucet,Gaël Cristofari
出处
期刊:Cancer Discovery
[American Association for Cancer Research]
日期:2023-12-12
卷期号:13 (12): 2502-2504
标识
DOI:10.1158/2159-8290.cd-23-1063
摘要
Summary: LINE-1 retrotransposons are frequently active in epithelial tumors. In a new study, Taylor, Wu and colleagues now describe that one of the proteins encoded by LINE-1 elements, ORF1p, is detected in the bloodstream of patients with cancer, and can be used as a noninvasive and multicancer biomarker for diagnosis or treatment monitoring. See related article by Taylor, Wu et al., p. 2532 (7).
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