A Comparative Study between Vacuum-Assisted Closure (VAC) versus Plaletets Rich Plasma (PRP) for Dressing of Diabetic Foot Ulcers

Abstract Background Diabetic foot ulcers are among the most generally perceived troubles of patients who have diabetes mellitus which isn't particularly controlled. It is commonly the outcome of poor glycemic control, stowed away neuropathy, periphery vascular sickness, or sad foot care. It is similarly one of the typical justification for osteomyelitis of the foot and evacuation of lower uttermost focuses. These ulcers are ordinarily in the space of the foot which encounters repetitive injury and strain sensations. Objective To evaluate the effect of plasma rich platelets versus vacuum-assisted-closure dressing in the improvement of the healing process in diabetic foot ulcer. Patients and Methods The survey included 40 patients who had continuous diabetic foot ulcer and were treated at the piece of Vascular and General an operation, Ain Scams School Facilities and Luxor Overall Crisis center, Cairo, Egypt. Starting from December 2021 to May 2022. Results Larger piece of the patients in both control and cases had discharge. (Patients with sickness or purulent delivery were barred from study). In our examination of 40 patients the ulcer size went from 6 to 15 cm2. The mean size in pack (A) was 9.48±1.91 cm2 and among Get-together (B) 9.56 ±1.87 cm2. In our survey we saw that recovering in cases or exploratory get-together took in a general sense less time when differentiated and bundle (A). The mean length of retouching in control pack was 7.3 ±1.91 weeks and mean term of recovering for pack (B) was 4.38±1.94 weeks. The probability regard (p regard) gained ensuing to applying unpaired t test for the above data arises to be 0.0001 which is really gigantic. Conclusion Our case series showed that PRP and VAC is a secured and strong treatment technique for consistent non-retouching ulcers. Using PRP to treat persevering wounds/ulcers might further develop patching, yet also thwart lower limit evacuations achieved by non-recovering injuries. Appropriately, further investigation and randomized controlled clinical starters on greater patient people are essential to endorse the results.