新生内膜
新生内膜增生
压电1
血管平滑肌
增生
细胞生物学
机械转化
基因剔除小鼠
内科学
医学
内分泌学
再狭窄
生物
机械敏感通道
离子通道
受体
平滑肌
支架
作者
F. Zhang,Jie Tang,Ying Lai,Shiqi Mo,Zhuomiao Lin,Qingqing Lei,Cong‐Cong Han,Andong Zhou,Xiao‐Fei Lv,Cheng Wang,Jing‐Song Ou,Jia‐Guo Zhou,Rui‐Ping Pang
摘要
These findings demonstrate a critical role of mechanosensitive Piezo1 channel in neointimal hyperplasia via modulating VSMC phenotype. Piezo1 channels may represent a novel therapeutic target for maladaptive vascular remodelling and occlusive vascular diseases.
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