纳米材料
锌
核化学
磷酸盐缓冲盐水
药物输送
材料科学
磷酸锌
纳米技术
化学
冶金
色谱法
作者
Wenwen Cheng,Jin Zhang,Na Lin,Ding Yuan,Shuai Zhang,Zhonggang Yang,Tianyi Cao
标识
DOI:10.1177/09592989241296437
摘要
Background Nanomaterials have applications in traditional Chinese medicine in the fields of medical equipment manufacturing, targeted transportation, and drug synergistic therapy. Objective The research aims to discuss the performance and performance of zinc-iron-based nanomaterials in medical drug delivery and synergistic drug therapy. Methods Using Prussian materials as precursors, magnetic zinc-iron nanomaterials were prepared by ZnCl 2 and K 3 [Fe (CN) 6 ]. Moreover, the morphology and composition of the material were analyzed. Results X-ray analysis was conducted on the prepared Zn 3 [Fe (CN) 6 ] 2 ·xH 2 O nanomaterials, and their purity met the design requirements. At the same time, drug loading analysis was conducted on Zn 3 [Fe(CN) 6 ] 2 ·xH 2 O, and the release of capsaicin reached 86.3% under a certain phosphate buffer solution. Meanwhile, Zn 3 [Fe (CN) 6 ] 2 ·xH2O loaded tetracycline could release up to 90% in phosphate buffer solution. Antibacterial tests were conducted on self-made Zn 3 [Fe(CN) 6 ] 2 ·xH 2 O samples and ZnFe 2 O 4 /ZnO. The Zn 3 [Fe(CN) 6 ] 2 ·xH 2 O samples showed a more significant inhibitory effect on cancer cells after loading with capsaicin. Conclusion The zinc-iron-based nanomaterials prepared by the research have excellent performance in drug loading and safety, indicating their significant potential for development in the medical field.
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