免疫系统
免疫检查点
乙型肝炎病毒
免疫学
病毒
医学
乙型肝炎
疾病
肝硬化
病毒学
免疫疗法
内科学
作者
Siyu Li,Na Li,Shujuan Yang,Hongkui Deng,Yanguo Li,Yixuan Wang,Junyou Yang,Jiaxin Lv,Dong Li,Guansen Yu,Xin Hou,Geng Wang
标识
DOI:10.1016/j.intimp.2022.108842
摘要
Chronic hepatitis B (CHB) is a contagious disease caused by the hepatitis B virus, which can damage the liver via cirrhosis or cancer. Existing CHB treatments are not completely effective; immune checkpoint inhibitors show potential hope for treating CHB, but their safety and efficacy need to be further validated. In this review, we introduce the mechanisms of CHB virus infection, the expression of immune checkpoints during CHB, and the treatments that are currently available. Finally, we discuss the possibilities for using immune checkpoint inhibitors to treat CHB.
科研通智能强力驱动
Strongly Powered by AbleSci AI