| 标题 |
 Structural elucidation, antioxidant and neuroprotective features of Physalis pubescens L. polysaccharide and its selenium-modified product 相关领域
抗氧化剂
化学
神经保护
硒
酸浆
多糖
传统医学
立体化学
植物
有机化学
生物
药理学
医学
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| 网址 | |
| DOI | |
| 其它 |
Abstract A novel polysaccharide, named as PPFP, was isolated from Physalis pubescens L. fruits with a molecular weight of 229.3 kDa. Further Structural characterisation revealed that PPFP comprised of rhamnose, arabinose, fucose, mannose and glucose, and the predominantly backbone is linked with 1 → 3- and 1 → 6-glycosidic bonds. Using the HNO3-Na2SeO3 method, the selenium-modified derivative (Se-PPFP) was successfully synthesised with higher bioavailability. FT-IR and NMR analyses confirmed selenium was attached to the Se-PPFP structure with the Se=O and O-Se-O forms. More specifically, selenium was bound to the C-6 bond on the D-pyranose of PPFP. Se-PPFP showed reduced molecular weight, looser microstructure and better thermal stability than PPFP. PPFP and Se-PPFP exhibited notable antioxidant and neuroprotective effects, with Se-PPFP being more significant. These findings suggest their potential as functional food antioxidants. |
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(2025-6-4)
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