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The Effect of Empagliflozin on Fluid Volume Status and Cardiac Adipose Tissue in Patients at Risk of Heart Failure: main Results from the Empire Prevent Metabolic Trial 相关领域
恩帕吉菲
医学
脂肪组织
心力衰竭
心脏病学
内科学
血管内容积状态
糖尿病
血流动力学
内分泌学
2型糖尿病
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Abstract: Background: Sodium glucose co‐transporter 2 (SGLT2) inhibitors have demonstrated cardiovascular and renal benefits in patients with type 2 diabetes, heart failure (HF) or chronic kidney disease (CKD), namely by reducing HF hospitalizations. Hypervolaemia and excessive epicardial adipose tissue (EAT) contribute to HF pathophysiology and are both prevalent in obesity. However, the effect of SGLT2 inhibitors in patients with obesity without diabetes and HF remains unknown. |
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