| 标题 |
TDCA and TUDCA improve glucose tolerance and reduce hepatic lipid accumulation in obese and diabetic models
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| 其它 | TDCA and TUDCA improve glucose tolerance and reduce hepatic lipid accumulation in obese and diabetic models a-d, GTT and the associated AUC values of DIO mice (a), STZ mice (b), ob/ob mice (c), db/db mice (d) after 3 weeks of TDCA and TUDCA treatments (five biological replicates for each group). e, f, Representative H&E-stained (e) and Oil Red O-stained (f) histological sections from livers of four mouse models (three biological replicates for each group). g-j, The hepatic triglycerides levels in DIO mice (g), STZ mice (h), ob/ob mice (i), db/db mice (j) after TDCA and TUDCA treatments (five biological replicates for each group). k-l, The hepatic triglycerides levels in CD-fed (k) and KDM-fed (l) mice after TDCA and TUDCA treatments (five biological replicates for each group). Error bars, s.e.m.; ns. not significant; *P < 0.05, **P < 0.01, ***P < 0.001 determined by one-way ANOVA with Tukey’s post-hoc test. Source data |
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(2025-6-4)
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