| 标题 |
 Healthy dietary patterns, genetic risk, and gastrointestinal cancer incident risk: a large-scale prospective cohort study 健康饮食模式、遗传风险和胃肠癌发病风险：一项大规模前瞻性队列研究
相关领域
医学
前瞻性队列研究
破折号
混淆
低风险
饮食与癌症
队列
内科学
比例危险模型
队列研究
人口学
置信区间
计算机科学
操作系统
社会学
|
| 网址 | |
| DOI | |
| 其它 |
Abstract Background: Dietary patterns have been associated with several cancers, especially gastrointestinal cancer (GIC). However, whether a healthy dietary pattern could modify the risk of GIC among people with different genetic backgrounds is not clear. Objective: The objective of the study was to investigate how dietary patterns and genetic susceptibility contribute to the risk of GIC independently and jointly. Methods: This large-scale prospective cohort study included 105,463 participants in UK Biobank who were aged 40-72 y and cancer-free at baseline. Dietary intake (Oxford WebQ) was used to calculate dietary pattern scores including dietary approach to stop hypertension (DASH) score and healthful plant-based diet index (hPDI). Genetic risk was quantified by a polygenic risk score (PRS) comprising 129 known GIC-associated loci. Cox proportional hazards regression was performed to estimate the associations of dietary patterns and PRS with GIC incidence after |
| 求助人 | |
| 下载 | 该求助完结已超 24 小时，文件已从服务器自动删除，无法下载。 |
|
温馨提示：该文献已被科研通 学术中心 收录，前往查看
科研通『学术中心』是文献索引库，收集文献的基本信息（如标题、摘要、期刊、作者、被引量等），不提供下载功能。如需下载文献全文，请通过文献求助获取。
|
PDF的下载单位、IP信息已删除
(2025-6-4)
无极微光
DW
null
殷勤的紫槐
mmmm
aaaa
152455
花开富贵
aajhajkahna
秋风
v0id
Criminology34
雨落千年
LYSM
乐空思
茶叶渣显示今天有雨
默默的紫真
04d
极限001
xing_xing
皖公网安备34019202002308
