| 标题 |
[高分] Perioperative vitamin C supplementation following total knee arthroplasty: A double-blind placebo-controlled randomized study
全膝关节置换术后围手术期补充维生素C：一项双盲安慰剂对照随机研究
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| 其它 |
Rudin D, Lengnick H, Zdravkovic V, Giesinger K, Ladurner A, Erschbamer M, Kuster M, Behrend H Swiss medical weekly, 2018, 148, 31S | added to CENTRAL: 30 June 2019 | 2019 Issue 06 Sourced from:Embase Abstract Introduction: Arthrofbrosis (AF) is a debilitating complication after total knee arthroplasty (TKA). This study was designed to determine whether perioperative supplementation of vitamin C (VC) improves range of motion (ROM) and reduces the risk of AF following TKA. Methods: Patients undergoing TKA were randomized to either oral VC (1000 mg daily) or placebo for 50 days, starting one day before surgery. VC plasma concentrations (VCc) were analysed in both patient groups before surgery, 4 and 7 days after surgery. The effect of VC supplementation was tested on Vitamin C plasma levels, ROM, AF, WOMAC and |
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