白色脂肪组织
脂肪组织
脂肪因子
昼夜节律
内分泌学
内分泌系统
内科学
食欲
生物
褐色脂肪组织
能源消耗
肥胖
瘦素
医学
激素
作者
Rianne van der Spek,Felix Kreier,Eric Fliers,Andries Kalsbeek
出处
期刊:Progress in Brain Research
日期:2012-01-01
卷期号:: 183-201
被引量:20
标识
DOI:10.1016/b978-0-444-59427-3.00011-3
摘要
Adipose tissue is an important endocrine organ. It is involved in the regulation of energy metabolism by secreting factors (adipokines) that regulate appetite, food intake, glucose disposal, and energy expenditure. Many of these adipokines display profound day/night rhythms, and accumulating evidence links disruption of these rhythms to metabolic diseases such as obesity and type 2 diabetes. Here, we briefly present the circadian system, describe the development of white adipose tissue (WAT) and its depot-specific characteristics and innervation, we discuss energy storage in WAT and, lastly, review recent findings that link circadian rhythmicity to adipose tissue biology and obesity.
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