Harnessing Visible Light for the Synthesis of N‐Aryl Oxazolidines: Organocatalyzed Tandem Decarboxylation‐Cyclization

Abstract Herein, we have developed an organophotocatalyzed, visible‐light mediated tandem decarboxylation‐cyclization method. The Eosin‐Y as organophotocatalyst drives photoredox tandem protocol to construct C−N, C−O, and C−C bonds in a single operation. The reaction mechanism proceeds through decarboxylation followed by amino alcohol intermediate formation from N ‐arylglycine and formaldehyde followed by cyclization with another formaldehyde delivers N ‐arylloxazolidine derivatives.