The Brazilian Society of Surgical Oncology (SBCO) Guidelines for the Treatment of Exocrine Pancreatic Insufficiency in Cancer Patients

ABSTRACT Exocrine pancreatic insufficiency (EPI) in oncology patients requires careful attention due to its clinical significance and frequent underdiagnosis. This narrative review and Guideline established by the Brazilian Society of Surgical Oncology suggest a practical approach to diagnosis and pancreatic enzyme replacement therapy (PERT). This promising approach can improve symptoms, nutritional status, and quality of life, potentially positively impacting survival in unresectable pancreatic cancer and postsurgical settings.