Nanoparticle Based CT Contrast Agents

The increasing significance of computed tomography (CT) which is one of the most widely used radiological methods in biomedical imaging, has accelerated the development of nanoparticles as next-generation CT contrast agents. Nanoparticles are predicted to play a significant role in the future of medical diagnostics due to their several benefits over conventional contrast agents, such as longer blood circulation time, regulated biological clearance pathways, and precise molecular targeting capabilities. The basic design concepts of nanoparticle-based CT contrast agents will be described in this chapter in comparison to iodine and other commercial products with in vivo and in vitro experiment.