CXCR6 sustains TRM-driven psoriasis relapse by CXCL16 chemotaxis and curcumol targeting

These research findings further validate the critical role of TRM cells in the relapse of psoriasis and suggest the potential value of curcumol as a CXCR6-targeted therapeutic agent in preventing the relapse of psoriasis. This study integrates mechanistic exploration with translational innovation, providing a new therapeutic strategy to address the clinical challenge of psoriasis relapse.