CUTANEOUS MANIFESTATIONS OF MONOCYTIC LEUKEMIA

THE PURPOSE of this study is to review 50 cases of monocytic leukemia of the Schilling type which have been observed at Cleveland Clinic Foundation Hospital since 1933. The majority of the patients were admitted to the medical service of Dr. Russell Haden, who made the hematologic diagnosis of monocytic leukemia in all cases. Histopathologic changes in cutaneous lesions of the specific type were studied in selected cases. The symptoms and clinical course of the disease are discussed briefly, and special consideration is given to the incidence and characteristics of cutaneous lesions observed. Detailed discussion of the hematology, which properly belongs in the province of a hematologist, was considered to be beyond the scope of this study. Suffice it to state that careful hematologic studies were made in each case. Previous observers have emphasized that certain types of mucocutaneous lesions occur oftener in monocytic leukemia than in the lymphatic or