Nano-Sized Copper Oxide Modified Carbon Paste Electrodes as an Amperometric Sensor for Amikacin

Abstract A novel nano-sized copper oxide modified carbon paste electrode has been fabricated to determine the amikacin by cyclic voltammetry and amperometry. The oxidation current of the amikacin on nano-sized copper oxide modified carbon paste electrode was about 40 times higher than that on bulk CuO modified carbon paste electrode. The curve of i vs. concentration was linear in the range of 2–200 µM of the amikacin concentration with a correlation coefficient of 0.998. The detection limit was ca. 1 µM of amikacin with the signal to noise ratio of 3.